STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0066Sulfate adenylate transferase, subunit 2 (cysD); Similar to SP:Q10599 PID:1322409 percent identity: 28.80; identified by sequence similarity; putative; In the C-terminal section; belongs to the PAPS reductase family. (480 aa)    
Predicted Functional Partners:
MJ_1241
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1241.
  
 
 0.962
cobA
uroporphyrin-III C-methyltransferase (cobA); Catalyzes both methylations at C-2 and C-7 of uroporphyrinogen III leading to precorrin-1 and precorrin-2; their oxidative esterification gives respectively factor I octamethyl ester and sirohydrochlorin.
 
  
 0.804
wtpB
Sulfate transport system permease protein (cysT); Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Probably responsible for the translocation of the substrate across the membrane (By similarity).
  
  
 0.784
hcp
[6Fe-6S] prismane-containing protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
  
 0.771
MJ_0981
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 28.18; identified by sequence similarity; putative.
 
     0.646
MJ_0140
Conserved hypothetical protein; Involved in the archaeal biosynthesis of heme. Catalyzes the oxiation of precorrin-2 into sirohydroclorin (By similarity). Belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
  
 0.572
MJ_0065
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 48.48; identified by sequence similarity; putative.
       0.569
cbiX
Conserved hypothetical protein; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.
  
  
 0.569
MJ_0067
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0067.
       0.565
MJ_0021
Conserved hypothetical protein; Similar to GP:1707810 percent identity: 43.12; identified by sequence similarity; putative.
  
     0.483
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.