Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_0084CODH nickel-insertion accessory protein (cooC); Similar to GP:1498749 percent identity: 33.33; identified by sequence similarity; putative. (249 aa)    
Predicted Functional Partners:
cdhE
acetyl-CoA decarbonylase/synthase, subunit gamma (cdhE); Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
 
  
 0.820
cdhD
acetyl-CoA decarbonylase/synthase, subunit delta (cdhD); Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.
 
  
 0.805
cdhC1
Carbon monoxide dehydrogenase, subunit alpha; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.
 
  
 0.799
cdhC2
acetyl-CoA decarbonylase/synthase, subunit beta (cdhC); Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.
 
  
 0.794
MJ_0085
Iron transport periplasmic binding protein, putative (ceuE); Similar to PID:1107531 percent identity: 25.10; identified by sequence similarity; putative.
 
     0.722
cooS
Carbon monoxide dehydrogenase, catalytic subunit (cooS); CODH oxidizes carbon monoxide coupled, via CooF, to the reduction of a hydrogen cation by a hydrogenase (possibly CooH).
 
   
 0.603
MJ_0087
Hemin permease (hemU); Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
       0.520
MJ_0086
Unspecified methyltransferase; Similar to PIR:S21265 percent identity: 25.50; identified by sequence similarity; putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
 
     0.503
MJ_0089
Ferric enterobactin transport ATP-binding protein; Similar to SP:P23878 GB:X57471 PID:41432 GB:U00096 PID:1778504 percent identity: 33.07; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
 
     0.479
cdhA
acetyl-CoA decarbonylase/synthase, subunit alpha (cdhA); Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
 
  
 0.436
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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