Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
suhBExtragenic suppressor (suhB); Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, both D and L isomers of inositol-1-phosphate (I-1-P), 2'-AMP, pNPP, beta-glycerol phosphate, and alpha-D-glucose-1- phosphate. Cannot hydrolyze glucose-6-phosphate, fructose-6-phosphate, NAD(+) or 5'-AMP. May be involved in the biosynthesis of a unique osmolyte, di-myo-inositol 1,1-phosphate. (252 aa)    
Predicted Functional Partners:
MJ_0110
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0110.
       0.889
gap
Glyceraldehyde 3-phosphate dehydrogenase; Similar to SP:P10618 PID:149792 percent identity: 60.00; identified by sequence similarity; putative.
     
 0.843
secD
Protein translocase, subunit SECD (secD); Involved in protein export.
  
  
 0.818
nusA
Putative transcription termination-antitermination factor (NusA); Participates in transcription termination. Belongs to the NusA family.
  
   0.788
spt5
LSU ribosomal protein L24A; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
 
 0.769
rpoK
DNA-directed RNA polymerase, subunit K (rpoK); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
  
   0.755
prs
Ribose-phosphate pyrophosphokinase, (prsA); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). It can also use dATP as diphosphoryl donor.
  
  
 0.733
hisB
Imidazoleglycerol-phosphate dehydrogenase/histidinol-phosphatase (hisB); Similar to SP:P06987 GB:X03416 PID:41696 PID:41711 GB:U00096 percent identity: 47.09; identified by sequence similarity; putative.
  
  
 0.721
rps10
SSU ribosomal protein S10P (rpsJ); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 
 0.720
eif5a
Translation initiation factor aIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
  
 0.717
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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