STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0115Conserved hypothetical protein; Similar to GB:S61233 PID:385925 GB:AE000666 percent identity: 48.98; identified by sequence similarity; putative. (155 aa)    
Predicted Functional Partners:
arfB
Conserved hypothetical protein; Catalyzes the hydrolysis of the formamide of 2-amino-5- formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy); Belongs to the creatininase superfamily. FAPy deformylase family.
  
    0.931
MJ_0144
Conserved hypothetical protein; Similar to GB:S61233 PID:385923 GB:AE000666 percent identity: 36.10; identified by sequence similarity; putative.
      0.909
nop10
Conserved hypothetical protein; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA; Belongs to the NOP10 family.
       0.654
eif2a
Translation initiation factor aIF-2, subunit alpha (aif2A); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
       0.654
MJ_1130
O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...]
       0.512
MJ_0227
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 40.07; identified by sequence similarity; putative.
       0.431
MJ_1453
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1453; To M.thermoautotrophicum MTH863.
       0.431
mrtD
Methyl coenzyme M reductase II, operon protein D (mtrD); Similar to GB:X70765 PID:488816 percent identity: 53.12; identified by sequence similarity; putative.
       0.401
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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