Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0119Carbon monoxide dehydrogenase gamma subunit (cdhE) isolog; Similar to PID:1002692 SP:Q50539 percent identity: 42.86; identified by sequence similarity; putative. (224 aa)    
Predicted Functional Partners:
MJ_0120
Urease accessory protein (ureG); Similar to GB:L24101 SP:P42871 PID:431755 percent identity: 34.53; identified by sequence similarity; putative.
 
    0.997
MJ_0121
SN-glycerol-3-phosphate transport ATP-binding protein (ugpC); Similar to SP:P10907 GB:U00039 PID:43249 PID:912455 GB:U00096 percent identity: 32.54; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
 
    0.997
comA
Conserved hypothetical protein; Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL).
 
    0.962
hypB
Hydrogenase expression/formation protein (hypB); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion; Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.
  
    0.829
MJ_1681
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 46.61; identified by sequence similarity; putative.
 
     0.778
MJ_0865
Conserved hypothetical protein; Similar to PID:1061002 percent identity: 34.05; identified by sequence similarity; putative.
 
     0.624
thrC
Threonine synthase (thrC); Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
       0.575
MJ_0658
Hypothetical protein; Invalid gene; identified by GeneMark; putative; M. jannaschii predicted coding region MJ0658; To M.thermoautotrophicum MTH238.
 
     0.568
MJ_1361
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 41.18; identified by sequence similarity; putative.
 
     0.486
cdhA
acetyl-CoA decarbonylase/synthase, subunit alpha (cdhA); Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
 
     0.460
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.