Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0120Urease accessory protein (ureG); Similar to GB:L24101 SP:P42871 PID:431755 percent identity: 34.53; identified by sequence similarity; putative. (233 aa)    
Predicted Functional Partners:
MJ_0121
SN-glycerol-3-phosphate transport ATP-binding protein (ugpC); Similar to SP:P10907 GB:U00039 PID:43249 PID:912455 GB:U00096 percent identity: 32.54; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
  
 0.999
MJ_0119
Carbon monoxide dehydrogenase gamma subunit (cdhE) isolog; Similar to PID:1002692 SP:Q50539 percent identity: 42.86; identified by sequence similarity; putative.
 
    0.997
comA
Conserved hypothetical protein; Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL).
  
    0.960
hypA
Hydrogenase expression/formation protein (hypA); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.886
MJ_0993
Hydrogenase expression/formation protein (hypD); Similar to SP:P31903 GB:X70183 PID:38775 percent identity: 42.46; identified by sequence similarity; putative; Belongs to the HypD family.
  
  
 0.849
MJ_0200
Hydrogenase expression/formation protein (hypC); Similar to GB:L23970 SP:P31881 GB:X63650 PID:39244 PID:398010 percent identity: 40.00; identified by sequence similarity; putative; Belongs to the HupF/HypC family.
  
  
 0.742
MJ_1681
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 46.61; identified by sequence similarity; putative.
 
     0.701
MJ_0278
Peptidyl-prolyl cis-trans isomerase, FKBP-type rotamase (slyD); Catalyzes the cis-trans isomerization of peptidyl prolyl bonds and accelerates protein folding. Also exhibits chaperone-like activity; Belongs to the FKBP-type PPIase family.
    
 
 0.653
MJ_0825
Peptidyl-prolyl cis-trans isomerase, FKBP-type rotamase (slyD); Catalyzes the cis-trans isomerization of peptidyl prolyl bonds and accelerates protein folding (By similarity). Also exhibits chaperone-like activity. Belongs to the FKBP-type PPIase family.
    
 
 0.653
hypF
Hydrogenase expression regulatory protein (hypF); Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
     
 0.564
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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