MJ_0130 protein (Methanocaldococcus jannaschii)

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MJ_0130

Type I restriction-modification enzyme 2, S subunit; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified, the DNA is cut. When the target site is hemimethylated, the complex acts as a mai [...] (343 aa)

Predicted Functional Partners:

MJ_0132

0.990

MJ_1220

0.975

MJ_1214

0.901

MJ_0124

0.899

MJ_0131

0.749

mjaIVMP

0.546

Your Current Organism:

Methanocaldococcus jannaschii

NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MJ_0124	MJ_0130	MJ_0124	MJ_0130	Type I restriction-modification enzyme 2, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 32.31; identified by sequence similarity; putative; To M.jannaschii MJ1214.	Type I restriction-modification enzyme 2, S subunit; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified, the DNA is cut. When the target site is hemimethylated, the complex acts as a mai [...]	0.899
MJ_0124	MJ_0132	MJ_0124	MJ_0132	Type I restriction-modification enzyme 2, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 32.31; identified by sequence similarity; putative; To M.jannaschii MJ1214.	Type I restriction-modification enzyme 2, M subunit; Similar to GB:L25415 PID:496158 percent identity: 39.36; identified by sequence similarity; putative; Belongs to the N4/N6-methyltransferase family.	0.981
MJ_0124	MJ_1220	MJ_0124	MJ_1220	Type I restriction-modification enzyme 2, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 32.31; identified by sequence similarity; putative; To M.jannaschii MJ1214.	Type I restriction-modification enzyme 1, M subunit; Similar to GB:L25415 PID:496158 percent identity: 32.85; identified by sequence similarity; putative.	0.981
MJ_0130	MJ_0124	MJ_0130	MJ_0124	Type I restriction-modification enzyme 2, S subunit; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified, the DNA is cut. When the target site is hemimethylated, the complex acts as a mai [...]	Type I restriction-modification enzyme 2, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 32.31; identified by sequence similarity; putative; To M.jannaschii MJ1214.	0.899
MJ_0130	MJ_0131	MJ_0130	MJ_0131	Type I restriction-modification enzyme 2, S subunit; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified, the DNA is cut. When the target site is hemimethylated, the complex acts as a mai [...]	Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0131.	0.749
MJ_0130	MJ_0132	MJ_0130	MJ_0132	Type I restriction-modification enzyme 2, S subunit; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified, the DNA is cut. When the target site is hemimethylated, the complex acts as a mai [...]	Type I restriction-modification enzyme 2, M subunit; Similar to GB:L25415 PID:496158 percent identity: 39.36; identified by sequence similarity; putative; Belongs to the N4/N6-methyltransferase family.	0.990
MJ_0130	MJ_1214	MJ_0130	MJ_1214	Type I restriction-modification enzyme 2, S subunit; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified, the DNA is cut. When the target site is hemimethylated, the complex acts as a mai [...]	Type I restriction-modification enzyme 1, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 27.55; identified by sequence similarity; putative.	0.901
MJ_0130	MJ_1220	MJ_0130	MJ_1220	Type I restriction-modification enzyme 2, S subunit; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified, the DNA is cut. When the target site is hemimethylated, the complex acts as a mai [...]	Type I restriction-modification enzyme 1, M subunit; Similar to GB:L25415 PID:496158 percent identity: 32.85; identified by sequence similarity; putative.	0.975
MJ_0130	mjaIVMP	MJ_0130	MJ_1328	Type I restriction-modification enzyme 2, S subunit; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified, the DNA is cut. When the target site is hemimethylated, the complex acts as a mai [...]	Modification methylase, type II R/M system; This methylase recognizes the double-stranded sequence GTNNAC, causes specific methylation on ? on both strands, and protects the DNA from cleavage by the MjaIV endonuclease.	0.546
MJ_0131	MJ_0130	MJ_0131	MJ_0130	Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0131.	Type I restriction-modification enzyme 2, S subunit; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified, the DNA is cut. When the target site is hemimethylated, the complex acts as a mai [...]	0.749
MJ_0131	MJ_0132	MJ_0131	MJ_0132	Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0131.	Type I restriction-modification enzyme 2, M subunit; Similar to GB:L25415 PID:496158 percent identity: 39.36; identified by sequence similarity; putative; Belongs to the N4/N6-methyltransferase family.	0.702
MJ_0132	MJ_0124	MJ_0132	MJ_0124	Type I restriction-modification enzyme 2, M subunit; Similar to GB:L25415 PID:496158 percent identity: 39.36; identified by sequence similarity; putative; Belongs to the N4/N6-methyltransferase family.	Type I restriction-modification enzyme 2, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 32.31; identified by sequence similarity; putative; To M.jannaschii MJ1214.	0.981
MJ_0132	MJ_0130	MJ_0132	MJ_0130	Type I restriction-modification enzyme 2, M subunit; Similar to GB:L25415 PID:496158 percent identity: 39.36; identified by sequence similarity; putative; Belongs to the N4/N6-methyltransferase family.	Type I restriction-modification enzyme 2, S subunit; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified, the DNA is cut. When the target site is hemimethylated, the complex acts as a mai [...]	0.990
MJ_0132	MJ_0131	MJ_0132	MJ_0131	Type I restriction-modification enzyme 2, M subunit; Similar to GB:L25415 PID:496158 percent identity: 39.36; identified by sequence similarity; putative; Belongs to the N4/N6-methyltransferase family.	Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0131.	0.702
MJ_0132	MJ_1214	MJ_0132	MJ_1214	Type I restriction-modification enzyme 2, M subunit; Similar to GB:L25415 PID:496158 percent identity: 39.36; identified by sequence similarity; putative; Belongs to the N4/N6-methyltransferase family.	Type I restriction-modification enzyme 1, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 27.55; identified by sequence similarity; putative.	0.981
MJ_0132	mjaIVMP	MJ_0132	MJ_1328	Type I restriction-modification enzyme 2, M subunit; Similar to GB:L25415 PID:496158 percent identity: 39.36; identified by sequence similarity; putative; Belongs to the N4/N6-methyltransferase family.	Modification methylase, type II R/M system; This methylase recognizes the double-stranded sequence GTNNAC, causes specific methylation on ? on both strands, and protects the DNA from cleavage by the MjaIV endonuclease.	0.561
MJ_1214	MJ_0130	MJ_1214	MJ_0130	Type I restriction-modification enzyme 1, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 27.55; identified by sequence similarity; putative.	Type I restriction-modification enzyme 2, S subunit; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified, the DNA is cut. When the target site is hemimethylated, the complex acts as a mai [...]	0.901
MJ_1214	MJ_0132	MJ_1214	MJ_0132	Type I restriction-modification enzyme 1, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 27.55; identified by sequence similarity; putative.	Type I restriction-modification enzyme 2, M subunit; Similar to GB:L25415 PID:496158 percent identity: 39.36; identified by sequence similarity; putative; Belongs to the N4/N6-methyltransferase family.	0.981
MJ_1214	MJ_1220	MJ_1214	MJ_1220	Type I restriction-modification enzyme 1, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 27.55; identified by sequence similarity; putative.	Type I restriction-modification enzyme 1, M subunit; Similar to GB:L25415 PID:496158 percent identity: 32.85; identified by sequence similarity; putative.	0.988
MJ_1220	MJ_0124	MJ_1220	MJ_0124	Type I restriction-modification enzyme 1, M subunit; Similar to GB:L25415 PID:496158 percent identity: 32.85; identified by sequence similarity; putative.	Type I restriction-modification enzyme 2, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 32.31; identified by sequence similarity; putative; To M.jannaschii MJ1214.	0.981

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