STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
truBCentromere/microtubule-binding protein (cbf5); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. (336 aa)    
Predicted Functional Partners:
nop10
Conserved hypothetical protein; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA; Belongs to the NOP10 family.
   
 0.999
MJ_0694
Conserved hypothetical protein; Similar to SP:Q12499 PID:1420682 PID:940841 percent identity: 43.15; identified by sequence similarity; putative.
 
 
 0.997
MJ_0782.1
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 48.08; identified by sequence similarity; putative; To M.thermoautotrophicum MTH886.
   
 0.990
infB
Translation initiation factor aIF-2 (infB); Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity).
 
 
 0.987
rpl7ae
LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs; Belongs to the eukaryotic ribosomal protein eL8 family.
 
 0.986
cmk
Cytidylate kinase (cmk); Similar to SP:P38493 GB:U11687 PID:533105 PID:1146214 GB:AL009126 percent identity: 33.12; identified by sequence similarity; putative.
     0.969
truA
Pseudouridylate synthase I (truA); Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
 
 
 0.959
rpl24
LSU ribosomal protein L24P (rplX); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
 
 
 0.949
MJ_0149
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0149.
       0.948
rps15
SSU ribosomal protein S15P (rpsO); Similar to GP:297071 percent identity: 48.34; identified by sequence similarity; putative.
 
 
 0.947
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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