Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ptr1Transcriptional regulator, putative; Participates in positive as well as negative regulation of transcription. Binds to its own promoter. (148 aa)    
Predicted Functional Partners:
MJ_0150
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0150; Belongs to the M.jannaschii MJ0150/MJ0739/MJ0745/MJ1460/MJ1642 family.
       0.931
truB
Centromere/microtubule-binding protein (cbf5); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
       0.565
MJ_0147
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0147; Belongs to the archaeal ATPase family.
       0.556
MJ_0149
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0149.
       0.556
cdhC1
Carbon monoxide dehydrogenase, subunit alpha; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.
       0.429
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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