STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0202Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 40.14; identified by sequence similarity; putative. (304 aa)    
Predicted Functional Partners:
purM
Phosphoribosylformylglycinamidine cyclo-ligase (purM); Similar to GB:J02732 SP:P12043 PID:143371 GB:AL009126 percent identity: 39.76; identified by sequence similarity; putative.
       0.803
MJ_0201
Lipoprotein B (lppB); Similar to GB:L42023 SP:P44832 PID:1005617 PID:1220788 PID:1204952 percent identity: 27.82; identified by sequence similarity; putative.
 
     0.613
purF
Amidophosphoribosyltransferase (purF); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
     
 0.526
mjaIIIM
Modification methylase, type II R/M system 2; This methylase recognizes the double-stranded sequence GATC, causes specific methylation on A-2 on both strands, and protects the DNA from cleavage by the MjaIII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family.
     
 0.504
MJ_0578
Iron-sulfer cluster binding protein; Similar to SP:P80168 percent identity: 49.02; identified by sequence similarity; putative.
 
     0.490
MJ_0200
Hydrogenase expression/formation protein (hypC); Similar to GB:L23970 SP:P31881 GB:X63650 PID:39244 PID:398010 percent identity: 40.00; identified by sequence similarity; putative; Belongs to the HupF/HypC family.
       0.455
purE
Phosphoribosylaminoimidazole carboxylase, (purE); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.431
MJ_0917
Conserved hypothetical protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes the phosphorylation and dephosphorylation of NAD and NADP, respectively. Although it shows conflicting dual activities and is able to supply NADP, it seems that its physiological role is to prevent excess accumulation of NADP. Kinase can use ATP and other nucleoside triphosphates (UTP, TTP, CTP, GTP) as well as inorganic polyphosphate (poly(P)) as phosphoryl donors, however poly(P) is not considered to be the phys [...]
       0.431
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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