STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
enoEnolase (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)    
Predicted Functional Partners:
MJ_0108
Pyruvate kinase; Similar to GB:D13095 SP:Q02499 GB:X57859 PID:285623 percent identity: 38.82; identified by sequence similarity; putative.
  
 0.997
pgk
Phosphoglycerate kinase (pgk); Similar to GB:M55529 SP:P20971 PID:149808 percent identity: 56.76; identified by sequence similarity; putative; Belongs to the phosphoglycerate kinase family.
 
 
 0.991
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P).
  
 
 0.990
pgi
Glucose-6-phosphate isomerase; Catalyzes the isomerization of glucose-6-P to fructose-6-P.
  
 0.989
gap
Glyceraldehyde 3-phosphate dehydrogenase; Similar to SP:P10618 PID:149792 percent identity: 60.00; identified by sequence similarity; putative.
  
 
 0.974
rps9
SSU ribosomal protein S9P (rpsI); Similar to SP:P05763 GB:M76567 PID:148778 percent identity: 50.39; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.957
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
 
  
 0.955
apgM1
Phosphonopyruvate decarboxylase (bcpC); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.924
apgM2
BcpC phosphonopyruvate decarboxylase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.919
fbp
Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.909
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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