| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MJ_0235 | thiDN | MJ_0235 | MJ_0236 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0235. | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | 0.778 |
| MJ_0235 | trpD | MJ_0235 | MJ_0234 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0235. | Anthranilate synthase component II (trpD); Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.931 |
| guaAA | trpD | MJ_1575 | MJ_0234 | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | Anthranilate synthase component II (trpD); Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.919 |
| guaAA | trpE | MJ_1575 | MJ_1075 | GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP. | Anthranilate synthase component I (trpE); Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] | 0.924 |
| hisC | trpA | MJ_0955 | MJ_1038 | Histidinol-phosphate aminotransferase (hisC); Similar to SP:P06986 GB:U02071 GB:X03416 PID:41695 PID:41710 percent identity: 29.00; identified by sequence similarity; putative. | Tryptophan synthase alpha subunit (trpA); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.899 |
| hisC | trpB | MJ_0955 | MJ_1037 | Histidinol-phosphate aminotransferase (hisC); Similar to SP:P06986 GB:U02071 GB:X03416 PID:41695 PID:41710 percent identity: 29.00; identified by sequence similarity; putative. | Tryptophan synthase beta subunit (trpB); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.651 |
| hisC | trpC | MJ_0955 | MJ_0918 | Histidinol-phosphate aminotransferase (hisC); Similar to SP:P06986 GB:U02071 GB:X03416 PID:41695 PID:41710 percent identity: 29.00; identified by sequence similarity; putative. | Indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (trpC); Similar to SP:P18304 PID:149042 percent identity: 42.65; identified by sequence similarity; putative; Belongs to the TrpC family. | 0.614 |
| hisC | trpD | MJ_0955 | MJ_0234 | Histidinol-phosphate aminotransferase (hisC); Similar to SP:P06986 GB:U02071 GB:X03416 PID:41695 PID:41710 percent identity: 29.00; identified by sequence similarity; putative. | Anthranilate synthase component II (trpD); Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.865 |
| hisC | trpE | MJ_0955 | MJ_1075 | Histidinol-phosphate aminotransferase (hisC); Similar to SP:P06986 GB:U02071 GB:X03416 PID:41695 PID:41710 percent identity: 29.00; identified by sequence similarity; putative. | Anthranilate synthase component I (trpE); Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] | 0.541 |
| hisC | trpF | MJ_0955 | MJ_0451 | Histidinol-phosphate aminotransferase (hisC); Similar to SP:P06986 GB:U02071 GB:X03416 PID:41695 PID:41710 percent identity: 29.00; identified by sequence similarity; putative. | Phosphoribosylanthranilate isomerase (trpF); Similar to GB:M83788 PID:149038 SP:P52563 percent identity: 41.23; identified by sequence similarity; putative; Belongs to the TrpF family. | 0.518 |
| hisC | trpG | MJ_0955 | MJ_0238 | Histidinol-phosphate aminotransferase (hisC); Similar to SP:P06986 GB:U02071 GB:X03416 PID:41695 PID:41710 percent identity: 29.00; identified by sequence similarity; putative. | Anthranilate synthase component II (trpG); Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high [...] | 0.593 |
| thiDN | MJ_0235 | MJ_0236 | MJ_0235 | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0235. | 0.778 |
| thiDN | trpD | MJ_0236 | MJ_0234 | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | Anthranilate synthase component II (trpD); Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.800 |
| thiDN | trpG | MJ_0236 | MJ_0238 | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | Anthranilate synthase component II (trpG); Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high [...] | 0.444 |
| trpA | hisC | MJ_1038 | MJ_0955 | Tryptophan synthase alpha subunit (trpA); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Histidinol-phosphate aminotransferase (hisC); Similar to SP:P06986 GB:U02071 GB:X03416 PID:41695 PID:41710 percent identity: 29.00; identified by sequence similarity; putative. | 0.899 |
| trpA | trpB | MJ_1038 | MJ_1037 | Tryptophan synthase alpha subunit (trpA); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Tryptophan synthase beta subunit (trpB); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |
| trpA | trpC | MJ_1038 | MJ_0918 | Tryptophan synthase alpha subunit (trpA); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (trpC); Similar to SP:P18304 PID:149042 percent identity: 42.65; identified by sequence similarity; putative; Belongs to the TrpC family. | 0.999 |
| trpA | trpD | MJ_1038 | MJ_0234 | Tryptophan synthase alpha subunit (trpA); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Anthranilate synthase component II (trpD); Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.996 |
| trpA | trpE | MJ_1038 | MJ_1075 | Tryptophan synthase alpha subunit (trpA); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Anthranilate synthase component I (trpE); Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] | 0.989 |
| trpA | trpF | MJ_1038 | MJ_0451 | Tryptophan synthase alpha subunit (trpA); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Phosphoribosylanthranilate isomerase (trpF); Similar to GB:M83788 PID:149038 SP:P52563 percent identity: 41.23; identified by sequence similarity; putative; Belongs to the TrpF family. | 0.989 |
