node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MJ_0233 | MJ_0235 | MJ_0233 | MJ_0235 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0233. | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0235. | 0.773 |
MJ_0233 | thiDN | MJ_0233 | MJ_0236 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0233. | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | 0.773 |
MJ_0233 | trpD | MJ_0233 | MJ_0234 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0233. | Anthranilate synthase component II (trpD); Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.778 |
MJ_0235 | MJ_0233 | MJ_0235 | MJ_0233 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0235. | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0233. | 0.773 |
MJ_0235 | thiDN | MJ_0235 | MJ_0236 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0235. | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | 0.779 |
MJ_0235 | trpD | MJ_0235 | MJ_0234 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0235. | Anthranilate synthase component II (trpD); Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.926 |
MJ_1178 | thiDN | MJ_1178 | MJ_0236 | Conserved hypothetical protein; Similar to SP:P42982 PID:755606 PID:1146237 GB:AL009126 percent identity: 26.36; identified by sequence similarity; putative; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | 0.869 |
MJ_1559 | thiDN | MJ_1559 | MJ_0236 | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency (By similarity); Belongs to the THEP1 NTPase family. | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | 0.909 |
MJ_1559 | thiL | MJ_1559 | MJ_0028 | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency (By similarity); Belongs to the THEP1 NTPase family. | Thiamine monphosphate kinase (thiL); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.900 |
thi4 | thiC | MJ_0601 | MJ_1026 | Thiamine biosynthetic enzyme (thi1); Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur; Belongs to the THI4 family. | Thiamine biosynthesis protein (thiC); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.949 |
thi4 | thiDN | MJ_0601 | MJ_0236 | Thiamine biosynthetic enzyme (thi1); Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur; Belongs to the THI4 family. | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | 0.935 |
thiC | thi4 | MJ_1026 | MJ_0601 | Thiamine biosynthesis protein (thiC); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Thiamine biosynthetic enzyme (thi1); Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur; Belongs to the THI4 family. | 0.949 |
thiC | thiDN | MJ_1026 | MJ_0236 | Thiamine biosynthesis protein (thiC); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | 0.998 |
thiC | thiL | MJ_1026 | MJ_0028 | Thiamine biosynthesis protein (thiC); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Thiamine monphosphate kinase (thiL); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.726 |
thiDN | MJ_0233 | MJ_0236 | MJ_0233 | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0233. | 0.773 |
thiDN | MJ_0235 | MJ_0236 | MJ_0235 | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0235. | 0.779 |
thiDN | MJ_1178 | MJ_0236 | MJ_1178 | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | Conserved hypothetical protein; Similar to SP:P42982 PID:755606 PID:1146237 GB:AL009126 percent identity: 26.36; identified by sequence similarity; putative; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | 0.869 |
thiDN | MJ_1559 | MJ_0236 | MJ_1559 | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency (By similarity); Belongs to the THEP1 NTPase family. | 0.909 |
thiDN | thi4 | MJ_0236 | MJ_0601 | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | Thiamine biosynthetic enzyme (thi1); Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur; Belongs to the THI4 family. | 0.935 |
thiDN | thiC | MJ_0236 | MJ_1026 | Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family. | Thiamine biosynthesis protein (thiC); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.998 |