STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dapADihydrodipicolinate synthase (dapA); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (289 aa)    
Predicted Functional Partners:
rps17e
SSU ribosomal protein S17E; Similar to SP:P02407 SP:P14127 PID:172458 PID:172460 PID:575695 percent identity: 51.61; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS17 family.
  
    0.997
aroQ
Chorismate mutase/prephenate dehydratase (pheA); Catalyzes the conversion of chorismate into prephenate via a Claisen rearrangement.
  
  
 0.997
MJ_0243
Conserved hypothetical protein; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity); Belongs to the GatC family.
  
  
 0.996
dapB
Dihydrodipicolinate reductase (dapB); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
 
 0.995
lysA
Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.989
asd
Aspartate-semialdehyde dehydrogenase (asd); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate. To a lesser extent, is able to use NAD instead of NADP. Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 
 0.984
hom
Homoserine dehydrogenase (hom); Similar to SP:P19582 GB:M23217 PID:558494 PID:809663 GB:AL009126 percent identity: 40.32; identified by sequence similarity; putative; Belongs to the homoserine dehydrogenase family.
  
 
 0.961
thyA
Thymidylate synthase (thyA); May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
  
  
 0.950
rps15
SSU ribosomal protein S15P (rpsO); Similar to GP:297071 percent identity: 48.34; identified by sequence similarity; putative.
  
  
 0.889
rnj
Conserved hypothetical protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
 
  
 0.853
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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