STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0248Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0248. (194 aa)    
Predicted Functional Partners:
MJ_0831
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 35.87; identified by sequence similarity; putative; To M.jannaschii MJ0977.
   
 
 0.978
rpl44e
LSU ribosomal protein L44E; Binds to the 23S rRNA.
  
    0.959
pcn
Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
  
  
 0.949
recJ
Conserved hypothetical protein; Single-stranded-DNA-specific exonuclease.
   
 
 0.949
rps27e
SSU ribosomal protein S27E; Similar to SP:P35997 SP:P38711 PID:2131116 PID:486271 PID:500694 percent identity: 42.59; identified by sequence similarity; putative.
       0.885
polB
DNA polymerase delta small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity); Belongs to the DNA polymerase delta/II small subunit family.
    
 
 0.825
MJ_1071
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1071; To M.jannaschii MJ0977 C-terminal region.
   
 
 0.806
priL
Hypothetical protein; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
     
 0.508
priS
DNA primase, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May [...]
     
 0.508
MJ_0652
Conserved hypothetical protein; Similar to SP:P54454 PID:1303790 GB:AL009126 percent identity: 44.71; identified by sequence similarity; putative.
   
    0.463
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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