Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpl44eLSU ribosomal protein L44E; Binds to the 23S rRNA. (94 aa)    
Predicted Functional Partners:
rps27e
SSU ribosomal protein S27E; Similar to SP:P35997 SP:P38711 PID:2131116 PID:486271 PID:500694 percent identity: 42.59; identified by sequence similarity; putative.
  
 
 0.999
rpl40e
LSU ribosomal protein L40E (CEP52); Similar to PIR:B48470 percent identity: 61.11; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family.
  
 0.999
rpl21e
LSU ribosomal protein L21E; Similar to GP:1215982 percent identity: 39.73; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL21 family.
 
 0.998
rpl31e
LSU ribosomal protein L31E; Similar to SP:P04649 PID:1431090 PID:4390 PID:625117 PID:625117 percent identity: 42.25; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL31 family.
  
 0.998
rpl23
LSU ribosomal protein L23P (rplW); Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
  
 0.998
rps17e
SSU ribosomal protein S17E; Similar to SP:P02407 SP:P14127 PID:172458 PID:172460 PID:575695 percent identity: 51.61; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS17 family.
 
 
 0.998
rpl22
LSU ribosomal protein L22P (rplV); This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
   
 0.998
rpl32e
LSU ribosomal protein L32E; Similar to SP:P14549 PID:44765 percent identity: 56.82; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL32 family.
  
 0.998
rpl19e
LSU ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
  
 0.998
rpl18
LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
 0.998
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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