Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
comAConserved hypothetical protein; Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL). (251 aa)    
Predicted Functional Partners:
comB
Conserved hypothetical protein; Hydrolyzes both enantiomers of 2-phosphosulfolactate. Able to hydrolyze both enantiomers of 2-hydroxycarboxylic acids with pseudosymmetric centers of inversion. Specifically hydrolyzes (S)- phospholactate and (S)-phosphoglycerate.
 
 
 0.992
MJ_0121
SN-glycerol-3-phosphate transport ATP-binding protein (ugpC); Similar to SP:P10907 GB:U00039 PID:43249 PID:912455 GB:U00096 percent identity: 32.54; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
  
    0.974
MJ_0119
Carbon monoxide dehydrogenase gamma subunit (cdhE) isolog; Similar to PID:1002692 SP:Q50539 percent identity: 42.86; identified by sequence similarity; putative.
 
    0.962
MJ_0120
Urease accessory protein (ureG); Similar to GB:L24101 SP:P42871 PID:431755 percent identity: 34.53; identified by sequence similarity; putative.
  
    0.960
hypB
Hydrogenase expression/formation protein (hypB); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion; Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.
  
    0.826
MJ_0664
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0664.
  
    0.823
pgk2
2-phosphoglycerate kinase (2pgk); Similar to GB:X70785 PID:467751 percent identity: 47.02; identified by sequence similarity; putative.
      
 0.646
MJ_1623
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1623.
   
    0.530
MJ_1241
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1241.
  
  
 0.471
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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