STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0284Conserved hypothetical protein; Similar to GP:1707764 percent identity: 31.50; identified by sequence similarity; putative. (219 aa)    
Predicted Functional Partners:
MJ_0285
Small heat shock protein (hsp20); Chaperone that confers thermal protection to other proteins; Belongs to the small heat shock protein (HSP20) family.
       0.590
bioB
Biotin synthetase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
    0.537
pus10
Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
 
   
 0.524
MJ_1016
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1016.
  
  
 0.509
MJ_0206
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 50.38; identified by sequence similarity; putative.
   
    0.465
cfbE
Conserved hypothetical protein; Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the activation the g-propionate side chain of 15,17(3)-seco-F430-17(3)-acid (seco-F430) for intramolecular C-C bond formation to yield the carbocyclic F ring of coenzyme F430. Belongs to the MurCDEF family.
   
    0.461
rpl10e
Ubiquinol-cytochrome C reductase complex, subunitVI requiring protein; Similar to GB:Z15157 SP:Q08770 PID:17584 PID:17682 PID:576963 percent identity: 43.90; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uL16 family.
  
    0.455
dph2
Conserved hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family.
     
 0.436
rpoL
DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
       0.431
MJ_0388
Conserved hypothetical protein; Similar to SP:P15886 PID:44739 percent identity: 45.74; identified by sequence similarity; putative.
       0.431
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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