Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_0285Small heat shock protein (hsp20); Chaperone that confers thermal protection to other proteins; Belongs to the small heat shock protein (HSP20) family. (147 aa)    
Predicted Functional Partners:
ths
Thermosome (ths); Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
  
  
 0.842
glnA
Glutamine synthetase (glnA); Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Beta-glutamate is a much poorer substrate than alpha-glutamate.
   
 
 0.784
rpl10e
Ubiquinol-cytochrome C reductase complex, subunitVI requiring protein; Similar to GB:Z15157 SP:Q08770 PID:17584 PID:17682 PID:576963 percent identity: 43.90; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uL16 family.
  
 
 0.737
MJ_1156
Cell division control protein 48 (cdc48), AAA family; Similar to GB:X79560 SP:P46464 PID:517390 percent identity: 57.53; identified by sequence similarity; putative; Belongs to the AAA ATPase family. CDC48 subfamily.
  
 
 0.730
MJ_1417
ATP-dependent protease LA, putative (lon); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Degrades polypeptides processively (By similarity).
  
  
 0.716
rfcS
Activator 1 (replication factor C), 35 KD subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily.
   
 
 0.693
MJ_1408
GTP-binding protein, member of GTP1/OBG-family; Similar to PID:1151233 percent identity: 30.46; identified by sequence similarity; putative; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
     
 0.661
MJ_0284
Conserved hypothetical protein; Similar to GP:1707764 percent identity: 31.50; identified by sequence similarity; putative.
       0.590
MJ_0927
Conserved hypothetical protein; DNA-binding protein exhibiting the ability to bind to both single-stranded and double-stranded DNA; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
   
 
 0.565
htpX
Heat shock protein HtpX, possibly protease (htpX); Similar to GB:M58470 SP:P23894 PID:146412 GB:U00096 PID:1736470 percent identity: 34.96; identified by sequence similarity; putative; Belongs to the peptidase M48B family.
     
 0.534
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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