STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fdhDFormate dehydrogenase (fdhD); Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family. (227 aa)    
Predicted Functional Partners:
MJ_0294
Large helicase-related protein (LHR), probably RNA helicase; Similar to GP:1707782 percent identity: 51.90; identified by sequence similarity; putative; Belongs to the helicase family.
       0.926
MJ_0006
Formate dehydrogenase, alpha subunit; Similar to GB:J02581 SP:P06131 PID:149708 percent identity: 41.56; identified by sequence similarity; putative; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
  
 0.900
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A (mobA); Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 
 
 
 0.897
moaA
Molybdenum cofactor biosynthesis protein (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
 0.878
MJ_0717
Molybdopterin converting factor, subunit 2 (moaE); Similar to GB:X70420 SP:P30749 PID:42012 GB:U00096 PID:1787003 percent identity: 31.52; identified by sequence similarity; putative; To Synechocystis PCC 6803 slr0903.
 
  
 0.754
moaC
Molybdenum cofactor biosynthesis protein (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
  
 0.752
mobB
Molybdopterin-guanine dinucleotide biosynthesis protein B (mobB); GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor, and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor. May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD. Displays a weak intrinsic GTPase activity (By similarity); Belongs to the MobB family.
 
  
 0.684
MJ_0652
Conserved hypothetical protein; Similar to SP:P54454 PID:1303790 GB:AL009126 percent identity: 44.71; identified by sequence similarity; putative.
       0.617
MJ_1632
Coenzyme PQQ synthesis protein (pqqE); Similar to SP:P27507 PID:809708 percent identity: 27.45; identified by sequence similarity; putative.
  
  
 0.609
MJ_0296
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0296.
       0.577
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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