node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MJ_0107 | MJ_0301 | MJ_0107 | MJ_0301 | Dihydropteroate synthase; Unknown. Does not possess dihydropteroate synthase (DHPS) activity since it does not catalyze the condensation of 6- hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) and 4- aminobenzoate to form 7,8-dihydropteroate. | Conserved hypothetical protein; Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin-6- methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor in the biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT). To a lesser extent, is able to condense beta-RFA-P with another arylamine, 1-(4-aminophenyl)-1-deoxy-D-ribitol (APDR), to form 7,8-dihydropterin- 6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol. Dephosphorylated beta- RFA-P is not a substrate; [...] | 0.853 |
MJ_0107 | mptE | MJ_0107 | MJ_1634 | Dihydropteroate synthase; Unknown. Does not possess dihydropteroate synthase (DHPS) activity since it does not catalyze the condensation of 6- hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) and 4- aminobenzoate to form 7,8-dihydropteroate. | Conserved hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. | 0.492 |
MJ_0107 | ribH | MJ_0107 | MJ_0303 | Dihydropteroate synthase; Unknown. Does not possess dihydropteroate synthase (DHPS) activity since it does not catalyze the condensation of 6- hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) and 4- aminobenzoate to form 7,8-dihydropteroate. | Riboflavin synthase beta chain (ribH); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.765 |
MJ_0107 | tpiA | MJ_0107 | MJ_1528 | Dihydropteroate synthase; Unknown. Does not possess dihydropteroate synthase (DHPS) activity since it does not catalyze the condensation of 6- hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) and 4- aminobenzoate to form 7,8-dihydropteroate. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P). | 0.572 |
MJ_0301 | MJ_0107 | MJ_0301 | MJ_0107 | Conserved hypothetical protein; Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin-6- methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor in the biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT). To a lesser extent, is able to condense beta-RFA-P with another arylamine, 1-(4-aminophenyl)-1-deoxy-D-ribitol (APDR), to form 7,8-dihydropterin- 6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol. Dephosphorylated beta- RFA-P is not a substrate; [...] | Dihydropteroate synthase; Unknown. Does not possess dihydropteroate synthase (DHPS) activity since it does not catalyze the condensation of 6- hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) and 4- aminobenzoate to form 7,8-dihydropteroate. | 0.853 |
MJ_0301 | MJ_0448 | MJ_0301 | MJ_0448 | Conserved hypothetical protein; Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin-6- methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor in the biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT). To a lesser extent, is able to condense beta-RFA-P with another arylamine, 1-(4-aminophenyl)-1-deoxy-D-ribitol (APDR), to form 7,8-dihydropterin- 6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol. Dephosphorylated beta- RFA-P is not a substrate; [...] | Conserved hypothetical protein; Similar to PID:577190 percent identity: 29.38; identified by sequence similarity; putative; Belongs to the metallo-beta-lactamase superfamily. | 0.918 |
MJ_0301 | MJ_0578 | MJ_0301 | MJ_0578 | Conserved hypothetical protein; Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin-6- methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor in the biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT). To a lesser extent, is able to condense beta-RFA-P with another arylamine, 1-(4-aminophenyl)-1-deoxy-D-ribitol (APDR), to form 7,8-dihydropterin- 6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol. Dephosphorylated beta- RFA-P is not a substrate; [...] | Iron-sulfer cluster binding protein; Similar to SP:P80168 percent identity: 49.02; identified by sequence similarity; putative. | 0.482 |
MJ_0301 | MJ_0579 | MJ_0301 | MJ_0579 | Conserved hypothetical protein; Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin-6- methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor in the biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT). To a lesser extent, is able to condense beta-RFA-P with another arylamine, 1-(4-aminophenyl)-1-deoxy-D-ribitol (APDR), to form 7,8-dihydropterin- 6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol. Dephosphorylated beta- RFA-P is not a substrate; [...] | Cell division inhibitor minD-like; Similar to GB:M95582 SP:Q01464 GB:M96343 PID:142859 PID:143216 percent identity: 31.79; identified by sequence similarity; putative; To M.jannaschii MJ0578. | 0.412 |
MJ_0301 | MJ_1477 | MJ_0301 | MJ_1477 | Conserved hypothetical protein; Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin-6- methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor in the biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT). To a lesser extent, is able to condense beta-RFA-P with another arylamine, 1-(4-aminophenyl)-1-deoxy-D-ribitol (APDR), to form 7,8-dihydropterin- 6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol. Dephosphorylated beta- RFA-P is not a substrate; [...] | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1477. | 0.706 |
MJ_0301 | hisE | MJ_0301 | MJ_0302 | Conserved hypothetical protein; Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin-6- methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor in the biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT). To a lesser extent, is able to condense beta-RFA-P with another arylamine, 1-(4-aminophenyl)-1-deoxy-D-ribitol (APDR), to form 7,8-dihydropterin- 6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol. Dephosphorylated beta- RFA-P is not a substrate; [...] | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (hisIE); Similar to SP:P06989 GB:D43637 GB:U02072 GB:X03974 PID:41700 percent identity: 30.43; identified by sequence similarity; putative. | 0.629 |
MJ_0301 | mptE | MJ_0301 | MJ_1634 | Conserved hypothetical protein; Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin-6- methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor in the biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT). To a lesser extent, is able to condense beta-RFA-P with another arylamine, 1-(4-aminophenyl)-1-deoxy-D-ribitol (APDR), to form 7,8-dihydropterin- 6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol. Dephosphorylated beta- RFA-P is not a substrate; [...] | Conserved hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. | 0.903 |
MJ_0301 | ribH | MJ_0301 | MJ_0303 | Conserved hypothetical protein; Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin-6- methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor in the biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT). To a lesser extent, is able to condense beta-RFA-P with another arylamine, 1-(4-aminophenyl)-1-deoxy-D-ribitol (APDR), to form 7,8-dihydropterin- 6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol. Dephosphorylated beta- RFA-P is not a substrate; [...] | Riboflavin synthase beta chain (ribH); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.434 |
MJ_0301 | tpiA | MJ_0301 | MJ_1528 | Conserved hypothetical protein; Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin-6- methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor in the biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT). To a lesser extent, is able to condense beta-RFA-P with another arylamine, 1-(4-aminophenyl)-1-deoxy-D-ribitol (APDR), to form 7,8-dihydropterin- 6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol. Dephosphorylated beta- RFA-P is not a substrate; [...] | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P). | 0.684 |
MJ_0448 | MJ_0301 | MJ_0448 | MJ_0301 | Conserved hypothetical protein; Similar to PID:577190 percent identity: 29.38; identified by sequence similarity; putative; Belongs to the metallo-beta-lactamase superfamily. | Conserved hypothetical protein; Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin-6- methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor in the biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT). To a lesser extent, is able to condense beta-RFA-P with another arylamine, 1-(4-aminophenyl)-1-deoxy-D-ribitol (APDR), to form 7,8-dihydropterin- 6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol. Dephosphorylated beta- RFA-P is not a substrate; [...] | 0.918 |
MJ_0448 | MJ_0578 | MJ_0448 | MJ_0578 | Conserved hypothetical protein; Similar to PID:577190 percent identity: 29.38; identified by sequence similarity; putative; Belongs to the metallo-beta-lactamase superfamily. | Iron-sulfer cluster binding protein; Similar to SP:P80168 percent identity: 49.02; identified by sequence similarity; putative. | 0.458 |
MJ_0448 | mptE | MJ_0448 | MJ_1634 | Conserved hypothetical protein; Similar to PID:577190 percent identity: 29.38; identified by sequence similarity; putative; Belongs to the metallo-beta-lactamase superfamily. | Conserved hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. | 0.903 |
MJ_0578 | MJ_0301 | MJ_0578 | MJ_0301 | Iron-sulfer cluster binding protein; Similar to SP:P80168 percent identity: 49.02; identified by sequence similarity; putative. | Conserved hypothetical protein; Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin-6- methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor in the biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT). To a lesser extent, is able to condense beta-RFA-P with another arylamine, 1-(4-aminophenyl)-1-deoxy-D-ribitol (APDR), to form 7,8-dihydropterin- 6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol. Dephosphorylated beta- RFA-P is not a substrate; [...] | 0.482 |
MJ_0578 | MJ_0448 | MJ_0578 | MJ_0448 | Iron-sulfer cluster binding protein; Similar to SP:P80168 percent identity: 49.02; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to PID:577190 percent identity: 29.38; identified by sequence similarity; putative; Belongs to the metallo-beta-lactamase superfamily. | 0.458 |
MJ_0578 | MJ_0579 | MJ_0578 | MJ_0579 | Iron-sulfer cluster binding protein; Similar to SP:P80168 percent identity: 49.02; identified by sequence similarity; putative. | Cell division inhibitor minD-like; Similar to GB:M95582 SP:Q01464 GB:M96343 PID:142859 PID:143216 percent identity: 31.79; identified by sequence similarity; putative; To M.jannaschii MJ0578. | 0.836 |
MJ_0579 | MJ_0301 | MJ_0579 | MJ_0301 | Cell division inhibitor minD-like; Similar to GB:M95582 SP:Q01464 GB:M96343 PID:142859 PID:143216 percent identity: 31.79; identified by sequence similarity; putative; To M.jannaschii MJ0578. | Conserved hypothetical protein; Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin-6- methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor in the biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT). To a lesser extent, is able to condense beta-RFA-P with another arylamine, 1-(4-aminophenyl)-1-deoxy-D-ribitol (APDR), to form 7,8-dihydropterin- 6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol. Dephosphorylated beta- RFA-P is not a substrate; [...] | 0.412 |