STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trxThioredoxin (trx); Acts to maintain redox homeostasis; functions as a protein disulfide reductase. (85 aa)    
Predicted Functional Partners:
MJ_1536
Thioredoxin reductase (trxB); Similar to GB:U02197 GB:L43967 SP:P47348 PID:1045780 percent identity: 38.93; identified by sequence similarity; putative.
  
 
 0.989
MJ_0636
Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative.
  
 0.982
MJ_0736
Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 0.962
MJ_0308
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 56.83; identified by sequence similarity; putative.
  
  
 0.944
rpl11
LSU ribosomal protein L11P (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
 
 0.791
rpoB2
DNA-directed RNA polymerase, subunit B'' (rpoB2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The B (B''+B' and beta) subunits have been implicated in DNA promoter recognition and also in nucleotide binding.
  
 
 0.786
rpoB1
DNA-directed RNA polymerase, subunit B' (rpoB1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The B (B''+B' and beta) subunits have been implicated in DNA promoter recognition and also in nucleotide binding.
  
 
 0.786
MJ_0306
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0306.
       0.778
rps6e
SSU ribosomal protein S6E; Similar to SP:P21509 percent identity: 39.84; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS6 family.
 
 
 0.776
nusA
Putative transcription termination-antitermination factor (NusA); Participates in transcription termination. Belongs to the NusA family.
   
   0.772
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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