STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speHConserved hypothetical protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (135 aa)    
Predicted Functional Partners:
speE
Spermidine synthase (speE); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
 0.999
pdaD
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 38.46; identified by sequence similarity; putative; Belongs to the PdaD family.
  
  
 0.984
mat
Conserved hypothetical protein; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
     
 0.913
MJ_0563
Modification methylase, type II R/M system; Similar to SP:P50192 percent identity: 35.29; identified by sequence similarity; putative.
     
  0.900
MJ_1200
Modification methylase, type II R/M system; Similar to SP:P05302 percent identity: 40.20; identified by sequence similarity; putative.
     
  0.900
MJ_0675
Conserved hypothetical protein; Similar to SP:P25125 PID:581802 PID:1655696 percent identity: 38.50; identified by sequence similarity; putative.
     0.778
speB
Agmatinase (speB); Catalyzes the formation of putrescine from agmatine.
     
 0.684
lysA
Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
     
 0.681
MJ_0454
Translation initiation factor aIF-2B, subunit delta (aIF2BD); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
     
 0.597
fucA
Fuculose-1-phosphate aldolase (fucA); Involved in the biosynthesis of the coenzyme F420 which requires phospholactate produced via the aldol cleavage of L-fuculose 1-phosphate and the NAD(+)-dependent oxidation of (S)-lactaldehyde. Catalyzes the reversible cleavage of L-fuculose 1- phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and S- lactaldehyde (Ref.2,. FucA possesses a high specificity for the dihydroxyacetone phosphate (DHAP), but accepts a great variety of different aldehydes such as DL-glyceraldehyde and glycolaldehyde.
     
 0.557
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.