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tyrS protein (Methanocaldococcus jannaschii) - STRING interaction network
"tyrS" - Tyrosine--tRNA ligase in Methanocaldococcus jannaschii
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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tyrSTyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (306 aa)    
Predicted Functional Partners:
trpS
Tryptophan--tRNA ligase; Similar to GB-X59892 GB-X67918 GB-X67919 GB-X67920 GB-X67921 percent identity- 31.02; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family (370 aa)
 
   
  0.964
ileS
Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily (1039 aa)
   
 
  0.962
tuf
Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (428 aa)
   
 
  0.959
leuS
Leucine--tRNA ligase; Similar to SP-P26637 PID-1370340 PID-1403549 PID-3508 percent identity- 35.17; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family (942 aa)
 
   
  0.946
metG
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (651 aa)
 
  0.930
gltX
Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction- glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (553 aa)
 
   
  0.921
pol
DNA polymerase; Similar to GB-D29671 PID-473967 PID-1620911 percent identity- 46.87; identified by sequence similarity; putative; Belongs to the DNA polymerase type-B family (1634 aa)
     
   
  0.865
serS
Type-2 serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (521 aa)
   
   
  0.862
hisS
Histidine--tRNA ligase; Similar to SP-P30053 percent identity- 35.44; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family (416 aa)
   
   
  0.857
eIF1A
Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity) (102 aa)
 
   
  0.838
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii DSM2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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