STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wecCUDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA). (427 aa)    
Predicted Functional Partners:
wecB
Lipopolysaccharide biosynthesis protein (wbpI); Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP- ManNAc), the activated donor of ManNAc residues; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
 
 
 0.999
MJ_0426
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0426.
       0.952
MJ_0427
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0427.
       0.952
MJ_1066
Spore coat polysaccharide biosynthesis protein C (spsC); Similar to GB:X73124 SP:P39623 PID:413989 GB:AL009126 percent identity: 54.97; identified by sequence similarity; putative.
  
  
 0.859
MJ_1113
N-acetylglucosamine-1-phosphate transferase; Similar to GB:D28748 SP:P39465 PID:506372 percent identity: 28.00; identified by sequence similarity; putative.
  
  
 0.821
MJ_0211
UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity). Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
  
 0.786
MJ_1055
Capsular polysaccharide biosynthesis protein I; Similar to GB:U10927 SP:P39858 PID:506705 percent identity: 50.32; identified by sequence similarity; putative; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
  
 0.688
MJ_1061
Capsular polysaccharide biosynthesis protein D; Similar to GB:U10927 SP:P39853 PID:506700 percent identity: 51.04; identified by sequence similarity; putative; Belongs to the polysaccharide synthase family.
  
  
 0.636
MJ_1054
UDP-glucose dehydrogenase, putative; Similar to GP:1651923 percent identity: 43.32; identified by sequence similarity; putative.
 
   
0.609
dapB
Dihydrodipicolinate reductase (dapB); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
       0.566
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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