node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MJ_0140 | MJ_0441 | MJ_0140 | MJ_0441 | Conserved hypothetical protein; Involved in the archaeal biosynthesis of heme. Catalyzes the oxiation of precorrin-2 into sirohydroclorin (By similarity). Belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Conserved hypothetical protein; Similar to GB:L42023 SP:P44070 PID:1006005 PID:1221007 PID:1205150 percent identity: 29.41; identified by sequence similarity; putative. | 0.471 |
MJ_0140 | MJ_1241 | MJ_0140 | MJ_1241 | Conserved hypothetical protein; Involved in the archaeal biosynthesis of heme. Catalyzes the oxiation of precorrin-2 into sirohydroclorin (By similarity). Belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1241. | 0.835 |
MJ_0140 | cbiX | MJ_0140 | MJ_0970 | Conserved hypothetical protein; Involved in the archaeal biosynthesis of heme. Catalyzes the oxiation of precorrin-2 into sirohydroclorin (By similarity). Belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Conserved hypothetical protein; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin. | 0.990 |
MJ_0140 | cobA | MJ_0140 | MJ_0965 | Conserved hypothetical protein; Involved in the archaeal biosynthesis of heme. Catalyzes the oxiation of precorrin-2 into sirohydroclorin (By similarity). Belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | uroporphyrin-III C-methyltransferase (cobA); Catalyzes both methylations at C-2 and C-7 of uroporphyrinogen III leading to precorrin-1 and precorrin-2; their oxidative esterification gives respectively factor I octamethyl ester and sirohydrochlorin. | 0.993 |
MJ_0440 | MJ_0441 | MJ_0440 | MJ_0441 | Conserved hypothetical protein; Similar to SP:P29085 GB:X67205 PID:45951 percent identity: 38.82; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to GB:L42023 SP:P44070 PID:1006005 PID:1221007 PID:1205150 percent identity: 29.41; identified by sequence similarity; putative. | 0.556 |
MJ_0441 | MJ_0140 | MJ_0441 | MJ_0140 | Conserved hypothetical protein; Similar to GB:L42023 SP:P44070 PID:1006005 PID:1221007 PID:1205150 percent identity: 29.41; identified by sequence similarity; putative. | Conserved hypothetical protein; Involved in the archaeal biosynthesis of heme. Catalyzes the oxiation of precorrin-2 into sirohydroclorin (By similarity). Belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.471 |
MJ_0441 | MJ_0440 | MJ_0441 | MJ_0440 | Conserved hypothetical protein; Similar to GB:L42023 SP:P44070 PID:1006005 PID:1221007 PID:1205150 percent identity: 29.41; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to SP:P29085 GB:X67205 PID:45951 percent identity: 38.82; identified by sequence similarity; putative. | 0.556 |
MJ_0441 | MJ_0649 | MJ_0441 | MJ_0649 | Conserved hypothetical protein; Similar to GB:L42023 SP:P44070 PID:1006005 PID:1221007 PID:1205150 percent identity: 29.41; identified by sequence similarity; putative. | NADH oxidase (nox); Catalyzes the four-electron reduction of molecular oxygen to water. | 0.463 |
MJ_0441 | MJ_1241 | MJ_0441 | MJ_1241 | Conserved hypothetical protein; Similar to GB:L42023 SP:P44070 PID:1006005 PID:1221007 PID:1205150 percent identity: 29.41; identified by sequence similarity; putative. | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1241. | 0.499 |
MJ_0441 | MJ_1623 | MJ_0441 | MJ_1623 | Conserved hypothetical protein; Similar to GB:L42023 SP:P44070 PID:1006005 PID:1221007 PID:1205150 percent identity: 29.41; identified by sequence similarity; putative. | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1623. | 0.557 |
MJ_0441 | aroC | MJ_0441 | MJ_1175 | Conserved hypothetical protein; Similar to GB:L42023 SP:P44070 PID:1006005 PID:1221007 PID:1205150 percent identity: 29.41; identified by sequence similarity; putative. | Chorismate synthase (aroC); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.462 |
MJ_0441 | cbiX | MJ_0441 | MJ_0970 | Conserved hypothetical protein; Similar to GB:L42023 SP:P44070 PID:1006005 PID:1221007 PID:1205150 percent identity: 29.41; identified by sequence similarity; putative. | Conserved hypothetical protein; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin. | 0.562 |
MJ_0441 | cobA | MJ_0441 | MJ_0965 | Conserved hypothetical protein; Similar to GB:L42023 SP:P44070 PID:1006005 PID:1221007 PID:1205150 percent identity: 29.41; identified by sequence similarity; putative. | uroporphyrin-III C-methyltransferase (cobA); Catalyzes both methylations at C-2 and C-7 of uroporphyrinogen III leading to precorrin-1 and precorrin-2; their oxidative esterification gives respectively factor I octamethyl ester and sirohydrochlorin. | 0.486 |
MJ_0441 | moaB | MJ_0441 | MJ_0167 | Conserved hypothetical protein; Similar to GB:L42023 SP:P44070 PID:1006005 PID:1221007 PID:1205150 percent identity: 29.41; identified by sequence similarity; putative. | Molybdenum cofactor biosynthesis protein (moaB); Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor. | 0.514 |
MJ_0441 | thyA | MJ_0441 | MJ_0511 | Conserved hypothetical protein; Similar to GB:L42023 SP:P44070 PID:1006005 PID:1221007 PID:1205150 percent identity: 29.41; identified by sequence similarity; putative. | Thymidylate synthase (thyA); May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. | 0.457 |
MJ_0649 | MJ_0441 | MJ_0649 | MJ_0441 | NADH oxidase (nox); Catalyzes the four-electron reduction of molecular oxygen to water. | Conserved hypothetical protein; Similar to GB:L42023 SP:P44070 PID:1006005 PID:1221007 PID:1205150 percent identity: 29.41; identified by sequence similarity; putative. | 0.463 |
MJ_1241 | MJ_0140 | MJ_1241 | MJ_0140 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1241. | Conserved hypothetical protein; Involved in the archaeal biosynthesis of heme. Catalyzes the oxiation of precorrin-2 into sirohydroclorin (By similarity). Belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.835 |
MJ_1241 | MJ_0441 | MJ_1241 | MJ_0441 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1241. | Conserved hypothetical protein; Similar to GB:L42023 SP:P44070 PID:1006005 PID:1221007 PID:1205150 percent identity: 29.41; identified by sequence similarity; putative. | 0.499 |
MJ_1241 | cbiX | MJ_1241 | MJ_0970 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1241. | Conserved hypothetical protein; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin. | 0.659 |
MJ_1241 | cobA | MJ_1241 | MJ_0965 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1241. | uroporphyrin-III C-methyltransferase (cobA); Catalyzes both methylations at C-2 and C-7 of uroporphyrinogen III leading to precorrin-1 and precorrin-2; their oxidative esterification gives respectively factor I octamethyl ester and sirohydrochlorin. | 0.917 |