STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rio1Conserved hypothetical protein; Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity). (290 aa)    
Predicted Functional Partners:
eIF1A
Translation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
  
 
 0.997
nob1
Ribosomal protein S15A isolog; Toxic component of a type II toxin-antitoxin (TA) system. Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end (By similarity); Belongs to the PINc/VapC protein family.
  
 0.997
rps6e
SSU ribosomal protein S6E; Similar to SP:P21509 percent identity: 39.84; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS6 family.
 
  0.990
rps11
SSU ribosomal protein S11P (rpsK); Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
 
 0.988
rps5
SSU ribosomal protein S5P (rpsE); With S4 and S12 plays an important role in translational accuracy.
  
 
 0.988
rps4
SSU ribosomal protein S4P (rpsD); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
  0.984
rio2
Conserved hypothetical protein; Similar to SP:P40160 PID:1302211 PID:600058 percent identity: 34.52; identified by sequence similarity; putative; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
  
 
0.975
rps3
SSU ribosomal protein S3P (rpsC); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 0.971
rps3ae
SSU ribosomal protein S3AE; Similar to GP:469248 percent identity: 29.17; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS1 family.
 
 
 0.969
rps15
SSU ribosomal protein S15P (rpsO); Similar to GP:297071 percent identity: 48.34; identified by sequence similarity; putative.
 
  0.960
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.