Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_0449Hypothetical transmembrane protein yeaB; Similar to GP:1708640 percent identity: 31.05; identified by sequence similarity; putative. (283 aa)    
Predicted Functional Partners:
MJ_0448
Conserved hypothetical protein; Similar to PID:577190 percent identity: 29.38; identified by sequence similarity; putative; Belongs to the metallo-beta-lactamase superfamily.
  
    0.948
mdh
L-lactate dehydrogenase EGAD|7256|705; Catalyzes the reversible oxidation of (S)-malate and (S)- sulfolactate to oxaloacetate and sulfopyruvate, respectively. Can use both NADH and NADPH, although activity is higher with NADPH. Oxidation of (S)-sulfolactate is observed only in the presence of NADP(+). Can also oxidize tartrate. Cannot reduce pyruvate, nor alpha-ketoglutarate. Belongs to the LDH/MDH superfamily.
  
    0.906
tgtA
Queuine tRNA-ribosyltransferase (tgtA); Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. Can also utilize guanine as substrate.
       0.663
MJ_0447
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0447.
       0.562
sla
S-layer structural protein; S-layer protein. The S-layer is a paracrystalline mono- layered assembly of proteins which coat the surface of the cell. Belongs to the Mj S-layer protein family.
   
    0.433
MJ_1036
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1036.
     
 0.421
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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