STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0488Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 47.74; identified by sequence similarity; putative. (158 aa)    
Predicted Functional Partners:
MJ_0489
Conserved hypothetical protein; Similar to PID:726060 GB:AE000666 percent identity: 36.80; identified by sequence similarity; putative.
  
  
 0.992
pheS
phenylalanyl-tRNA synthetase, subunit alpha (pheS); Similar to SP:P15625 PID:172947 PID:836732 percent identity: 40.91; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
  
    0.833
MJ_0785
Biotin synthetase, putative (bioB); Similar to GB:M27867 SP:P19206 PID:142591 PID:520750 percent identity: 27.43; identified by sequence similarity; putative.
     
 0.706
MJ_1251
Conserved hypothetical protein; Similar to PID:726072 percent identity: 37.75; identified by sequence similarity; putative; Belongs to the UPF0254 family.
     
 0.688
MJ_0693
Conserved hypothetical protein; Similar to PID:726058 GB:AE000666 percent identity: 44.93; identified by sequence similarity; putative.
     
 0.672
MJ_0927
Conserved hypothetical protein; DNA-binding protein exhibiting the ability to bind to both single-stranded and double-stranded DNA; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
       0.600
mdh
L-lactate dehydrogenase EGAD|7256|705; Catalyzes the reversible oxidation of (S)-malate and (S)- sulfolactate to oxaloacetate and sulfopyruvate, respectively. Can use both NADH and NADPH, although activity is higher with NADPH. Oxidation of (S)-sulfolactate is observed only in the presence of NADP(+). Can also oxidize tartrate. Cannot reduce pyruvate, nor alpha-ketoglutarate. Belongs to the LDH/MDH superfamily.
       0.592
MJ_0491
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 25.19; identified by sequence similarity; putative.
       0.592
MJ_0486
Conserved hypothetical protein; Similar to SP:P45476 PID:606150 GB:U00096 PID:2367204 percent identity: 29.79; identified by sequence similarity; putative.
       0.431
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: medium (56%) [HD]