STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0500Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 25.14; identified by sequence similarity; putative. (259 aa)    
Predicted Functional Partners:
aroA-2
3-phosphoshikimate-1-carboxyvinyltransferase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
       0.719
MJ_0501
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 37.24; identified by sequence similarity; putative.
  
    0.595
MJ_0085
Iron transport periplasmic binding protein, putative (ceuE); Similar to PID:1107531 percent identity: 25.10; identified by sequence similarity; putative.
 
    0.579
wtpB
Sulfate transport system permease protein (cysT); Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Probably responsible for the translocation of the substrate across the membrane (By similarity).
 
    0.567
wtpA
Conserved hypothetical protein; Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate (By similarity).
 
     0.550
MJ_1599
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1599.
  
    0.520
pfkC
Hypothetical protein; Catalyzes the phosphorylation of fructose 6-phosphate and D- glucose to fructose 1,6-bisphosphate and D-glucose 6-phosphate, respectively, using ADP as the phosphate donor; Belongs to the carbohydrate kinase PfkC family.
  
     0.462
pycA
Biotin carboxylase (accC); Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
       0.431
MJ_1559
Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency (By similarity); Belongs to the THEP1 NTPase family.
       0.431
pol
DNA polymerase B1; Similar to GB:D29671 PID:473967 PID:1620911 percent identity: 46.87; identified by sequence similarity; putative; Belongs to the DNA polymerase type-B family.
  
     0.427
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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