STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0505Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0505. (251 aa)    
Predicted Functional Partners:
MJ_0096
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0096.
   
    0.826
MJ_0504
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 61.08; identified by sequence similarity; putative.
       0.776
aksA
2-isopropylmalate synthase (leuA); Catalyzes the condensation of alpha-ketoglutarate and acetyl- CoA to form trans-homoaconitate. Can also catalyze the condensation of alpha-ketoadipate with acetyl-CoA to form (R)-homo(2)citrate, and the condensation of alpha-ketopimelate with acetyl-CoA to form (R)- homo(3)citrate; Belongs to the alpha-IPM synthase/homocitrate synthase family.
       0.671
aroA-2
3-phosphoshikimate-1-carboxyvinyltransferase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
       0.481
MJ_0501
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 37.24; identified by sequence similarity; putative.
  
    0.466
MJ_0420
O-antigen polymerase isolog; Similar to GB:M60066 SP:P26479 PID:154343 percent identity: 26.15; identified by sequence similarity; putative.
   
    0.464
MJ_1375
SpoVB isolog; Similar to GB:D26185 SP:P37555 PID:467446 GB:AL009126 percent identity: 23.61; identified by sequence similarity; putative.
  
    0.450
bioB
Biotin synthetase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
   
    0.433
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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