Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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MJ_0535Acetylpolyamine aminohydrolase (aphA); Putative deacetylase. (343 aa)    
Predicted Functional Partners:
MJ_1156
Cell division control protein 48 (cdc48), AAA family; Similar to GB:X79560 SP:P46464 PID:517390 percent identity: 57.53; identified by sequence similarity; putative; Belongs to the AAA ATPase family. CDC48 subfamily.
 
 
 0.966
rpl40e
LSU ribosomal protein L40E (CEP52); Similar to PIR:B48470 percent identity: 61.11; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family.
  
 0.892
smc
Chromosome segretation protein (smc1); Required for chromosome condensation and partitioning. Belongs to the SMC family.
   
 0.848
ndk
Nucleoside diphosphate kinase, (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 
 0.813
ths
Thermosome (ths); Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
  
 
 0.779
MJ_0941
Hypothetical protein; ORF; identified by GeneMark; putative; M. jannaschii predicted coding region MJ0941.
 
 
 0.768
MJ_1345
O-linked GlnNAc transferase; Similar to GB:AE000666 percent identity: 37.88; identified by sequence similarity; putative.
 
 
 0.768
tbp
Transcription initiation factor IID, TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
  
 0.747
rpl7ae
LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs; Belongs to the eukaryotic ribosomal protein eL8 family.
  
 
 
 0.743
MJ_0263
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 34.57; identified by sequence similarity; putative.
   
 0.734
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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