Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MJ_0558Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 41.96; identified by sequence similarity; putative. (261 aa)    
Predicted Functional Partners:
nep1
Conserved hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of pseudouridine at position 914 (Psi914) in 16S rRNA. Is not able to methylate uridine at this position.
       0.928
MJ_0623
Conserved hypothetical protein; Similar to GP:1673676 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the metallophosphoesterase superfamily. YfcE family.
       0.685
MJ_0037
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 37.05; identified by sequence similarity; putative.
       0.677
ef1b
Hypothetical protein; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
 
     0.662
MJ_1646
Pyrimidine biosynthesis protein, putative; Similar to GP:340170 percent identity: 31.30; identified by sequence similarity; putative; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
     0.637
mptD
Conserved hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
  
     0.599
MJ_1198
Conserved hypothetical protein; Similar to GB:L77117 PID:1591827 percent identity: 100.00; identified by sequence similarity; putative.
  
     0.582
surE
surE stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
       0.570
MJ_1401
Putative ATP dependent RNA helicase; Similar to SP:P32639 PID:603413 percent identity: 29.62; identified by sequence similarity; putative; Belongs to the DEAD box helicase family.
 
     0.564
nrpR
Conserved hypothetical protein; Transcriptional repressor of nitrogen fixation and assimilation genes. Binds to two tandem operators in the glnA and nif promoters, thereby blocking transcription of the genes. Belongs to the NrpR family.
  
     0.551
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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