Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
MJ_0580Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 44.55; identified by sequence similarity; putative. (118 aa)    
Predicted Functional Partners:
MJ_0579
Cell division inhibitor minD-like; Similar to GB:M95582 SP:Q01464 GB:M96343 PID:142859 PID:143216 percent identity: 31.79; identified by sequence similarity; putative; To M.jannaschii MJ0578.
 
  
 0.946
MJ_0578
Iron-sulfer cluster binding protein; Similar to SP:P80168 percent identity: 49.02; identified by sequence similarity; putative.
 
  
 0.940
MJ_1243
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 38.71; identified by sequence similarity; putative; Belongs to the UPF0251 family.
 
  
 0.728
cfbD
Vanadium nitrogenase-associated protein N; Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes both the six-electron reduction of the tetrahydroporphyrin ring system and the gamma-lactamization of the c- acetamide side chain of Ni-sirohydrochlorin a,c-diamide to yield 15,17(3)-seco-F430-17(3)-acid (seco-F430), the last intermediate in the biosynthesis of the coenzyme F430; Belongs to the NifD/NifK/NifE/NifN family.
  
 
 0.670
nifH
Nitrogenase iron protein (nifH); The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
  
  
 0.610
MJ_0283
Nucleotide-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
 
  
 0.543
MJ_0582
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 34.74; identified by sequence similarity; putative; To M.jannaschii MJ0766.
       0.481
MJ_0584
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 37.98; identified by sequence similarity; putative.
  
    0.475
MJ_0581
Conserved hypothetical protein; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase (By similarity). Has low thioredoxin activity in vitro (By similarity).
       0.468
wtpA
Conserved hypothetical protein; Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate (By similarity).
  
  
 0.443
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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