node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MJ_0106 | MJ_1210 | MJ_0106 | MJ_1210 | Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 38.16; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 46.03; identified by sequence similarity; putative. | 0.757 |
MJ_0106 | psmA | MJ_0106 | MJ_0591 | Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 38.16; identified by sequence similarity; putative. | Proteasome, subunit alpha (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The M.jannaschii proteasome is able to cleave oligopeptides after Glu, Asp, Tyr, Phe, Trp, slightly after Arg, but not after Ala. Thus, displays caspase-like and chymotrypsin-like activities and low level of trypsin- like activity. | 0.903 |
MJ_0106 | psmB | MJ_0106 | MJ_1237 | Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 38.16; identified by sequence similarity; putative. | Proteasome, subunit beta (psmB); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The M.jannaschii proteasome is able to cleave oligopeptides after Glu, Asp, Tyr, Phe, Trp, slightly after Arg, but not after Ala. Thus, displays caspase-like and chymotrypsin-like activities and low level of trypsin- like activity. | 0.792 |
MJ_0106 | rpl40e | MJ_0106 | MJ_0707 | Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 38.16; identified by sequence similarity; putative. | LSU ribosomal protein L40E (CEP52); Similar to PIR:B48470 percent identity: 61.11; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.410 |
MJ_0122 | psmA | MJ_0122 | MJ_0591 | Translation initiation factor aIF-2B, subunit delta, putative; Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO. | Proteasome, subunit alpha (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The M.jannaschii proteasome is able to cleave oligopeptides after Glu, Asp, Tyr, Phe, Trp, slightly after Arg, but not after Ala. Thus, displays caspase-like and chymotrypsin-like activities and low level of trypsin- like activity. | 0.752 |
MJ_0122 | psmB | MJ_0122 | MJ_1237 | Translation initiation factor aIF-2B, subunit delta, putative; Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO. | Proteasome, subunit beta (psmB); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The M.jannaschii proteasome is able to cleave oligopeptides after Glu, Asp, Tyr, Phe, Trp, slightly after Arg, but not after Ala. Thus, displays caspase-like and chymotrypsin-like activities and low level of trypsin- like activity. | 0.757 |
MJ_0592 | psmA | MJ_0592 | MJ_0591 | Conserved hypothetical protein; Similar to SP:Q07953 PID:1360328 percent identity: 33.53; identified by sequence similarity; putative; Belongs to the SDO1/SBDS family. | Proteasome, subunit alpha (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The M.jannaschii proteasome is able to cleave oligopeptides after Glu, Asp, Tyr, Phe, Trp, slightly after Arg, but not after Ala. Thus, displays caspase-like and chymotrypsin-like activities and low level of trypsin- like activity. | 0.814 |
MJ_0592 | rpl15e | MJ_0592 | MJ_0983 | Conserved hypothetical protein; Similar to SP:Q07953 PID:1360328 percent identity: 33.53; identified by sequence similarity; putative; Belongs to the SDO1/SBDS family. | LSU ribosomal protein L15E (rpl15); Similar to SP:P49403 PID:785060 percent identity: 54.74; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL15 family. | 0.938 |
MJ_0592 | rpl40e | MJ_0592 | MJ_0707 | Conserved hypothetical protein; Similar to SP:Q07953 PID:1360328 percent identity: 33.53; identified by sequence similarity; putative; Belongs to the SDO1/SBDS family. | LSU ribosomal protein L40E (CEP52); Similar to PIR:B48470 percent identity: 61.11; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.887 |
MJ_0639 | psmA | MJ_0639 | MJ_0591 | Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0639. | Proteasome, subunit alpha (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The M.jannaschii proteasome is able to cleave oligopeptides after Glu, Asp, Tyr, Phe, Trp, slightly after Arg, but not after Ala. Thus, displays caspase-like and chymotrypsin-like activities and low level of trypsin- like activity. | 0.860 |
MJ_1156 | pan | MJ_1156 | MJ_1176 | Cell division control protein 48 (cdc48), AAA family; Similar to GB:X79560 SP:P46464 PID:517390 percent identity: 57.53; identified by sequence similarity; putative; Belongs to the AAA ATPase family. CDC48 subfamily. | Proteasome regulatory AAA-ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20 [...] | 0.867 |
MJ_1156 | psmA | MJ_1156 | MJ_0591 | Cell division control protein 48 (cdc48), AAA family; Similar to GB:X79560 SP:P46464 PID:517390 percent identity: 57.53; identified by sequence similarity; putative; Belongs to the AAA ATPase family. CDC48 subfamily. | Proteasome, subunit alpha (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The M.jannaschii proteasome is able to cleave oligopeptides after Glu, Asp, Tyr, Phe, Trp, slightly after Arg, but not after Ala. Thus, displays caspase-like and chymotrypsin-like activities and low level of trypsin- like activity. | 0.864 |
MJ_1156 | psmB | MJ_1156 | MJ_1237 | Cell division control protein 48 (cdc48), AAA family; Similar to GB:X79560 SP:P46464 PID:517390 percent identity: 57.53; identified by sequence similarity; putative; Belongs to the AAA ATPase family. CDC48 subfamily. | Proteasome, subunit beta (psmB); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The M.jannaschii proteasome is able to cleave oligopeptides after Glu, Asp, Tyr, Phe, Trp, slightly after Arg, but not after Ala. Thus, displays caspase-like and chymotrypsin-like activities and low level of trypsin- like activity. | 0.854 |
MJ_1156 | rpl15e | MJ_1156 | MJ_0983 | Cell division control protein 48 (cdc48), AAA family; Similar to GB:X79560 SP:P46464 PID:517390 percent identity: 57.53; identified by sequence similarity; putative; Belongs to the AAA ATPase family. CDC48 subfamily. | LSU ribosomal protein L15E (rpl15); Similar to SP:P49403 PID:785060 percent identity: 54.74; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL15 family. | 0.786 |
MJ_1156 | rpl40e | MJ_1156 | MJ_0707 | Cell division control protein 48 (cdc48), AAA family; Similar to GB:X79560 SP:P46464 PID:517390 percent identity: 57.53; identified by sequence similarity; putative; Belongs to the AAA ATPase family. CDC48 subfamily. | LSU ribosomal protein L40E (CEP52); Similar to PIR:B48470 percent identity: 61.11; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.949 |
MJ_1210 | MJ_0106 | MJ_1210 | MJ_0106 | Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 46.03; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 38.16; identified by sequence similarity; putative. | 0.757 |
MJ_1210 | psmA | MJ_1210 | MJ_0591 | Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 46.03; identified by sequence similarity; putative. | Proteasome, subunit alpha (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The M.jannaschii proteasome is able to cleave oligopeptides after Glu, Asp, Tyr, Phe, Trp, slightly after Arg, but not after Ala. Thus, displays caspase-like and chymotrypsin-like activities and low level of trypsin- like activity. | 0.771 |
MJ_1210 | rpl40e | MJ_1210 | MJ_0707 | Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 46.03; identified by sequence similarity; putative. | LSU ribosomal protein L40E (CEP52); Similar to PIR:B48470 percent identity: 61.11; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.594 |
pan | MJ_1156 | MJ_1176 | MJ_1156 | Proteasome regulatory AAA-ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20 [...] | Cell division control protein 48 (cdc48), AAA family; Similar to GB:X79560 SP:P46464 PID:517390 percent identity: 57.53; identified by sequence similarity; putative; Belongs to the AAA ATPase family. CDC48 subfamily. | 0.867 |
pan | psmA | MJ_1176 | MJ_0591 | Proteasome regulatory AAA-ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20 [...] | Proteasome, subunit alpha (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The M.jannaschii proteasome is able to cleave oligopeptides after Glu, Asp, Tyr, Phe, Trp, slightly after Arg, but not after Ala. Thus, displays caspase-like and chymotrypsin-like activities and low level of trypsin- like activity. | 0.997 |