STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpl18aLSU ribosomal protein LXA; Similar to GB:X77509 SP:P38613 PID:453441 percent identity: 38.89; identified by sequence similarity; putative. (76 aa)    
Predicted Functional Partners:
rpl37ae
LSU ribosomal protein L37AE; Binds to the 23S rRNA.
  
 
 0.999
rpl21e
LSU ribosomal protein L21E; Similar to GP:1215982 percent identity: 39.73; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL21 family.
  
 0.998
eif6
Conserved hypothetical protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex; Belongs to the eIF-6 family.
  
 
 0.998
rpl31e
LSU ribosomal protein L31E; Similar to SP:P04649 PID:1431090 PID:4390 PID:625117 PID:625117 percent identity: 42.25; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL31 family.
  
 
 0.998
rpl22
LSU ribosomal protein L22P (rplV); This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
   
 0.998
rps19e
SSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
  
 
 0.998
rpl23
LSU ribosomal protein L23P (rplW); Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
   
 0.997
rps19
SSU ribosomal protein S19P (rpsS); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
 
 0.997
rps13
SSU ribosomal protein S13P (rpsM); Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family.
   
 
 0.997
rpl18e
LSU ribosomal protein L18E; Identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL18 family.
   
 0.997
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.