STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mjaIIIMModification methylase, type II R/M system 2; This methylase recognizes the double-stranded sequence GATC, causes specific methylation on A-2 on both strands, and protects the DNA from cleavage by the MjaIII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. (289 aa)    
Predicted Functional Partners:
mjaIIIR
Restriction enzyme, type II R/M system 2; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family.
   
 0.987
MJ_1200
Modification methylase, type II R/M system; Similar to SP:P05302 percent identity: 40.20; identified by sequence similarity; putative.
     
 0.900
mjaVIM
Modification methylase, type II R/M system; This methylase recognizes the double-stranded sequence CCGG, causes specific methylation on C-? on both strands, and protects the DNA from cleavage by the MjaVI endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.
  
  
 0.894
MJ_0597
Conserved hypothetical protein; Similar to PID:747640 GB:AE000666 percent identity: 24.23; identified by sequence similarity; putative.
   
   0.753
MJ_0599
Hypothetical protein; Invalid gene; identified by GeneMark; putative; M. jannaschii predicted coding region MJ0599.
       0.714
rpe
Pentose-5-phosphate-3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
 
    0.600
MJ_0596
Hypothetical protein; Invalid gene; identified by GeneMark; putative; M. jannaschii predicted coding region MJ0596.
       0.556
MJ_0202
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 40.14; identified by sequence similarity; putative.
     
 0.504
ndk
Nucleoside diphosphate kinase, (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
       0.431
thi4
Thiamine biosynthetic enzyme (thi1); Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur; Belongs to the THI4 family.
       0.402
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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