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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0612Chorismate mutase/prephenate dehydratase (tyrA); Similar to SP:P07023 PID:457110 GB:U00096 PID:1788952 percent identity: 33.46; identified by sequence similarity; putative; In the N-terminal section; belongs to the prephenate/arogenate dehydrogenase family. (446 aa)    
Predicted Functional Partners:
pheA
Chorismate mutase/prephenate dehydratase (pheA); Similar to SP:P43909 PID:683585 percent identity: 38.59; identified by sequence similarity; putative.
 
 0.997
aroQ
Chorismate mutase/prephenate dehydratase (pheA); Catalyzes the conversion of chorismate into prephenate via a Claisen rearrangement.
 
 
 0.984
hisC
Histidinol-phosphate aminotransferase (hisC); Similar to SP:P06986 GB:U02071 GB:X03416 PID:41695 PID:41710 percent identity: 29.00; identified by sequence similarity; putative.
    
 0.922
MJ_0001
Aspartate aminotransferase (aspB1); Similar to PID:1146246 SP:P53001 GB:AL009126 percent identity: 44.38; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
    
 0.921
aroA-2
3-phosphoshikimate-1-carboxyvinyltransferase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.766
aroC
Chorismate synthase (aroC); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
   
 0.745
hmd
H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenease (hmd); Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
      
 0.706
MJ_0611.1
Hypothetical protein; Brute Force ORF; identified by GeneMark; putative; M. jannaschii predicted coding region MJ0611.1.
       0.559
MJ_0611
Conserved hypothetical integral membrane protein; Similar to GP:1565238 percent identity: 34.56; identified by sequence similarity; putative; Belongs to the peptidase M50B family.
       0.547
aroE
Shikimate 5-dehydrogenase (aroE); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
     
 0.529
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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