STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MJ_0623Conserved hypothetical protein; Similar to GP:1673676 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the metallophosphoesterase superfamily. YfcE family. (192 aa)    
Predicted Functional Partners:
MJ_0624
Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons probably in the CO-dehydrogenase complex.
       0.919
purO
Conserved hypothetical protein; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP; Belongs to the archaeal IMP cyclohydrolase family.
       0.880
tfb
Transcription initiation factor IIB (TFIIB); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
 
    0.746
MJ_0736
Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.711
MJ_0558
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 41.96; identified by sequence similarity; putative.
       0.685
rlmE
Cell division protein FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
  
    0.675
MJ_0625
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0625; Belongs to the archaeal ATPase family.
       0.587
MJ_0942
ATP-dependent DNA helicase DinG, putative (dinG); Similar to GP:1736447 percent identity: 30.88; identified by sequence similarity; putative.
       0.584
MJ_0226
Conserved hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides xanthosine triphosphate (XTP), deoxyinosine triphosphate (dITP) and ITP. Probably functions as a house- cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Shows very low activity on GTP or dGTP, both of which are hydrolyzed more than 100-fold less efficiently than X [...]
  
  
 0.547
rfcS
Activator 1 (replication factor C), 35 KD subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily.
 
     0.454
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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