STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0634Conserved hypothetical protein; Similar to GB:L42023 SP:P44641 PID:1003549 PID:1222253 PID:1204581 percent identity: 27.59; identified by sequence similarity; putative; Belongs to the radical SAM superfamily. KamA family. (620 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase (dapB); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
     
 0.513
dapA
Dihydrodipicolinate synthase (dapA); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
     
 0.512
MJ_0635
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0635.
       0.450
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (bioA); Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
  
  
 0.450
MJ_1497
Acetylornithine deacetylase (argE); Similar to SP:P23908 GB:X55417 GB:X62807 PID:396304 PID:40955 percent identity: 26.01; identified by sequence similarity; putative.
 
  
 0.419
eif5a
Translation initiation factor aIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
     
 0.416
leuS
leucyl-tRNA synthetase (leuS); Similar to SP:P26637 PID:1370340 PID:1403549 PID:3508 percent identity: 35.17; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.409
secF
Protein translocase, subunit SECF (secF); Involved in protein export.
  
    0.402
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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