STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0642Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0642. (333 aa)    
Predicted Functional Partners:
hemB
Porphobilinogen synthase (hemB); Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
     
 0.807
cbiJ
Cobalamin biosynthesis protein (cbiJ); Catalyzes the reduction of the macrocycle of cobalt- precorrin-6A to cobalt-precorrin-6B.
  
  
 0.762
cbiG
Cobalamin biosynthesis protein (cbiG); Catalyzes the hydrolysis of the ring A acetate delta-lactone of cobalt-precorrin-5A resulting in the loss of the C-20 carbon and its attached methyl group in the form of acetaldehyde.
  
  
 0.759
cbiF
Cobalamin biosynthesis precorrin-3 methylase (cbiF); Catalyzes the methylation of C-11 in cobalt-precorrin-4 to form cobalt-precorrin-5A.
 
  
 0.684
MJ_0873
Ferric enterobactin transport ATP-binding protein; Similar to SP:P23878 GB:X57471 PID:41432 GB:U00096 PID:1778504 percent identity: 35.86; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
 
     0.679
cbiL
Cobalamin biosynthesis precorrin-2 methyltransferase (cbiL); Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.
  
  
 0.631
cbiH
Cobalamin biosynthesis precorrin-3 methylase (cbiH); Methyltransferase that likely catalyzes the ring contraction and methylation of C-17 in cobalt-factor III to form cobalt-factor IV. May also convert cobalt-precorrin-3 to cobalt-precorrin-4 (By similarity).
  
  
 0.611
MJ_0644
S-adenosylmethionine:2-demethylmenaquinone methyltransferase (menG); Similar to GB:L19201 SP:P32165 PID:305032 GB:U00096 PID:1336002 percent identity: 29.22; identified by sequence similarity; putative.
       0.598
cbiD
Cobalamin biosynthesis protein (cbiD); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
  
  
 0.597
MJ_0876
iron(III) dicitrate transport system permease protein; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
     0.590
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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