STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0644S-adenosylmethionine:2-demethylmenaquinone methyltransferase (menG); Similar to GB:L19201 SP:P32165 PID:305032 GB:U00096 PID:1336002 percent identity: 29.22; identified by sequence similarity; putative. (208 aa)    
Predicted Functional Partners:
fae-hps
D-arabino 3-hexulose 6-phosphate formaldehyde lyase isolog; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
 
   
 0.965
rpe
Pentose-5-phosphate-3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
    
  0.912
phi
Conserved hypothetical protein; Catalyzes the isomerization between 3-hexulose 6-phosphate and fructose 6-phosphate; Belongs to the SIS family. PHI subfamily.
    
  0.910
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
   
 
  0.904
MJ_0645
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 44.97; identified by sequence similarity; putative.
       0.895
MJ_0669
ATP-dependent RNA helicase, DEAD-family (deaD); Similar to GB:L42023 SP:P44586 PID:1003361 PID:1222156 PID:1204489 percent identity: 43.17; identified by sequence similarity; putative; Belongs to the DEAD box helicase family.
   
 
 0.767
flpA
Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
   
 
 0.767
MJ_1519
Exodeoxyribonuclease V (recD); Similar to GB:L42023 SP:P45158 PID:1007312 PID:1205560 PID:1221454 percent identity: 33.33; identified by sequence similarity; putative.
   
 
 0.767
MJ_0646
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 34.39; identified by sequence similarity; putative; Belongs to the UPF0305 family.
       0.695
hemB
Porphobilinogen synthase (hemB); Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
       0.623
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.