Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MJ_0651Protease IV (sppA); Similar to GB:L42023 SP:P45243 PID:1007737 PID:1221687 PID:1205776 percent identity: 34.91; identified by sequence similarity; putative; Belongs to the peptidase S49 family. (311 aa)    
Predicted Functional Partners:
MJ_0652
Conserved hypothetical protein; Similar to SP:P54454 PID:1303790 GB:AL009126 percent identity: 44.71; identified by sequence similarity; putative.
       0.939
MJ_1177
Conserved hypothetical protein; Similar to GB:M94110 SP:Q04454 PID:142791 percent identity: 24.44; identified by sequence similarity; putative.
 
   
 0.737
secD
Protein translocase, subunit SECD (secD); Involved in protein export.
 
   
 0.631
ftsY
Signal recognition particle, receptor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
     
 0.533
metG
methionyl-tRNA synthetase (metS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
     0.506
gatA
Amidase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln) (By similarity).
     
 0.478
fdhD
Formate dehydrogenase (fdhD); Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family.
     
 0.441
pyrF
Conserved hypothetical protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
       0.410
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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