STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0700Conserved hypothetical protein; Similar to SP:P11666 PID:41424 PID:882453 GB:U00096 PID:1789291 percent identity: 22.34; identified by sequence similarity; putative. (324 aa)    
Predicted Functional Partners:
polB
DNA polymerase delta small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity); Belongs to the DNA polymerase delta/II small subunit family.
 
    0.963
priL
Hypothetical protein; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
       0.955
MJ_0703
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (hisA2); Similar to SP:P05324 PID:150050 PID:44716 percent identity: 30.36; identified by sequence similarity; putative; Belongs to the HisA/HisF family.
       0.700
MJ_1650
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 31.03; identified by sequence similarity; putative.
  
    0.688
MJ_0699
Atrazine chlorohydrolase isolog; Similar to GP:1493840 percent identity: 28.15; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily.
     
 0.619
MJ_0703.1
Hypothetical protein; Brute Force ORF; identified by GeneMark; putative; M. jannaschii predicted coding region MJ0703.1.
       0.451
MJ_0832
Anaerobic ribonucleoside-triphosphate reductase (nrdD); Similar to SP:P28903 GB:L06097 GB:U06195 GB:Z46865 PID:146970 percent identity: 28.17; identified by sequence similarity; putative.
 
    0.410
MJ_0611
Conserved hypothetical integral membrane protein; Similar to GP:1565238 percent identity: 34.56; identified by sequence similarity; putative; Belongs to the peptidase M50B family.
 
   
 0.403
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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