Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
MJ_0709Conserved hypothetical protein; Similar to SP:P54181 PID:1256651 GB:AL009126 percent identity: 22.92; identified by sequence similarity; putative. (450 aa)    
Predicted Functional Partners:
trmG10
Conserved hypothetical protein; Catalyzes the adenosylmethionine-dependent methylation of the exocyclic amino group (N(2)) of guanosine at position 10 of various tRNAs. Acts via a two-step process that leads to the formation of either N(2)-monomethyl (m(2)G) or N(2)-dimethylguanosine (m(2)(2)G) (By similarity); Belongs to the methyltransferase superfamily. Trm-G10 family.
  
    0.911
tbp
Transcription initiation factor IID, TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
   
  
 0.842
gap
Glyceraldehyde 3-phosphate dehydrogenase; Similar to SP:P10618 PID:149792 percent identity: 60.00; identified by sequence similarity; putative.
  
  
 0.791
rpl15
LSU ribosomal protein L15P (rplO); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.720
rps6e
SSU ribosomal protein S6E; Similar to SP:P21509 percent identity: 39.84; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS6 family.
   
   0.689
rpl40e
LSU ribosomal protein L40E (CEP52); Similar to PIR:B48470 percent identity: 61.11; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family.
 
 
 
 0.686
rps17
SSU ribosomal protein S17P (rpsQ); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
 
 0.677
rpl24
LSU ribosomal protein L24P (rplX); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
 
 0.676
rpl23
LSU ribosomal protein L23P (rplW); Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
   
   0.663
MJ_0708
Conserved hypothetical protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family.
 
   
 0.619
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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