Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MJ_0715H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase-related protein (hmd); Similar to PID:1149527 SP:Q50840 percent identity: 29.86; identified by sequence similarity; putative; Belongs to the HMD family. (338 aa)    
Predicted Functional Partners:
MJ_0714
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 61.40; identified by sequence similarity; putative; To M.jannaschii MJ0310 and MJ1340.
  
    0.897
MJ_1339
Protein with ATP/GTP-binding site; Similar to SP:P04766 GB:X04399 PID:39954 percent identity: 32.65; identified by sequence similarity; putative; To M.thermoautotrophicum MTH765.
  
    0.876
MJ_0310
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 60.53; identified by sequence similarity; putative.
  
    0.731
MJ_1340
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 61.40; identified by sequence similarity; putative; To M.jannaschii MJ0310 and MJ0714.
  
    0.731
MJ_0716
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0716.
       0.660
MJ_0311
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0311.
  
    0.514
MJ_1389
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1389.
  
    0.514
hypF
Hydrogenase expression regulatory protein (hypF); Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
     
 0.462
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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