Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_0717Molybdopterin converting factor, subunit 2 (moaE); Similar to GB:X70420 SP:P30749 PID:42012 GB:U00096 PID:1787003 percent identity: 31.52; identified by sequence similarity; putative; To Synechocystis PCC 6803 slr0903. (119 aa)    
Predicted Functional Partners:
moaC
Molybdenum cofactor biosynthesis protein (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
 
 0.996
moaB
Molybdenum cofactor biosynthesis protein (moaB); Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor.
  
 
 0.980
trkA
TRK system potassium uptake protein (trkA); Part of a potassium transport system.
  
    0.895
MJ_1412
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 37.85; identified by sequence similarity; putative; Belongs to the UPF0288 family.
   
    0.888
MJ_0263
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 34.57; identified by sequence similarity; putative.
  
    0.838
MJ_0940
Transformation sensitive protein; Similar to GB:M86752 SP:P31948 PID:184565 percent identity: 30.84; identified by sequence similarity; putative.
  
    0.838
aroA
Conserved hypothetical protein; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. Can also catalyze the cleavage of fructose-1,6- bisphosphate (FBP) to glyceraldehyde-3-phosphate (GAP) and dihydroxyacetone phosphate (DHAP).
  
    0.831
moaA
Molybdenum cofactor biosynthesis protein (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
  
 0.822
mobB
Molybdopterin-guanine dinucleotide biosynthesis protein B (mobB); GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor, and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor. May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD. Displays a weak intrinsic GTPase activity (By similarity); Belongs to the MobB family.
 
 
 0.818
MJ_0718
Chromate resistance protein (chrA); Similar to GB:J05278 SP:P17551 PID:141913 percent identity: 27.60; identified by sequence similarity; putative.
 
   
 0.786
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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