STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0719RNase L inhibitor; Similar to PIR:S63672 percent identity: 48.74; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (600 aa)    
Predicted Functional Partners:
prf1
Peptide chain release factor aRF, subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
  
 
 0.992
eif2a
Translation initiation factor aIF-2, subunit alpha (aif2A); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
   
 
 0.947
rps6e
SSU ribosomal protein S6E; Similar to SP:P21509 percent identity: 39.84; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 
 0.943
rps3ae
SSU ribosomal protein S3AE; Similar to GP:469248 percent identity: 29.17; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 
 0.941
rps4e
SSU ribosomal protein S4E; Similar to SP:P14023 PID:44760 percent identity: 70.49; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS4 family.
  
 
 0.936
rps3
SSU ribosomal protein S3P (rpsC); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 
 0.934
rps17e
SSU ribosomal protein S17E; Similar to SP:P02407 SP:P14127 PID:172458 PID:172460 PID:575695 percent identity: 51.61; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS17 family.
 
   0.929
rps24e
SSU ribosomal protein S24E; Similar to SP:P19953 GB:X70117 PID:312779 percent identity: 42.57; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS24 family.
  
 
 0.928
rpl10
LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 
 0.928
rps12
SSU ribosomal protein S12P (rpsL); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
  
 
 0.925
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.