Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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oggConserved hypothetical protein; Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites). Has little specificity for the base opposite oxoG. (207 aa)    
Predicted Functional Partners:
MJ_0767
Conserved hypothetical protein; Similar to SP:P28910 PID:147625 PID:466617 GB:U00096 PID:1789892 percent identity: 23.48; identified by sequence similarity; putative; Belongs to the transcriptional regulatory CopG/NikR family.
       0.712
MJ_0725
Coenzyme F420-reducing hydrogenase, beta subunit; Similar to GB:J02914 SP:P19499 PID:149718 GB:AE000666 percent identity: 42.24; identified by sequence similarity; putative; Belongs to the FrhB family.
       0.546
rad50
Purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
  
   
 0.434
rps27e
SSU ribosomal protein S27E; Similar to SP:P35997 SP:P38711 PID:2131116 PID:486271 PID:500694 percent identity: 42.59; identified by sequence similarity; putative.
 
     0.411
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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