STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0731Iron-sulfur flavoprotein (isf); Redox-active protein probably involved in electron transport. Belongs to the SsuE family. Isf subfamily. (198 aa)    
Predicted Functional Partners:
MJ_0730
DNA/pantothenate metabolism flavoprotein-like; Similar to GB:L10328 SP:P24285 PID:290489 GB:U00096 PID:1790070 percent identity: 31.20; identified by sequence similarity; putative; To M.jannaschii MJ0208.
 
    0.886
rgy
Reverse gyrase, intein containing (rgy); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
      
 0.769
MJ_0732
Flavoprotein (fprA); Similar to PID:687617 percent identity: 40.62; identified by sequence similarity; putative.
  
  
 0.678
MJ_0734
Rubrerythrin (rr); May provide oxidative stress protection via catalytic reduction of intracellular hydrogen peroxide.
 
     0.551
purT
Phosphoribosylglycinamide formyltransferase 2 (purT); Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
  
    0.511
MJ_0733
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0733.
  
    0.510
MJ_0480
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 27.49; identified by sequence similarity; putative.
   
    0.497
MJ_0736
Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.466
MJ_0764
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0764.
 
    0.446
MJ_0106
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 38.16; identified by sequence similarity; putative.
 
    0.419
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.